|
|
linoleic_acid + O2 <=> (9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate
|
1.13.11.58
linoleate 9S-lipoxygenase
1.13.11.B6
|
–
–
|
|
BRENDA:
BR49245
KEGG:
R07057
MetaCyc:
RXN-8495
|
|
|
|
(8R,9Z,12Z)-8-hydroperoxy-9,12-octadecadienoate <=> (7S,8S,9Z,12Z)-7,8-dihydroxyoctadeca-9,12-dienoate
|
5.4.4.6
9,12-octadecadienoate 8-hydroperoxide 8S-isomerase
|
–
|
|
BRENDA:
BR49959
KEGG:
R07062
MetaCyc:
RXN-12758
|
|
|
|
linoleic_acid + O2 <=> (9Z,11E,13S)-13-hydroperoxy-9,11-octadecadienoate
|
1.13.11.12
linoleate 13S-lipoxygenase
1.13.11.31
arachidonate 12-lipoxygenase
1.13.11.33
arachidonate 15-lipoxygenase
1.13.11.34
arachidonate 5-lipoxygenase
|
–
–
–
–
|
|
BRENDA:
BR37113
KEGG:
R03626
MetaCyc:
LIPOXYGENASE-RXN
SABIO-RK:
3408
|
|
|
|
linoleic_acid + O2 + NADPH + H+ <=> (9Z)-12,13-epoxyoctadec-9-enoate + NADP+ + H2O
|
1.14.13
1.14.14
1.14.14.1
unspecific monooxygenase
|
–
–
–
|
|
KEGG:
R07056
|
|
|
|
linoleic_acid + 2 ferricytochrome_b5 + O2 + 2 H+ <=> crepenynate + 2 ferricytochrome_b5 + 2 H2O
|
1.14.19.39
acyl-lipid Delta12-acetylenase
|
–
|
|
KEGG:
R05740
|
|
|
|
(9Z)-12,13-epoxyoctadec-9-enoate + H2O <=> (9Z)-12,13-dihydroxyoctadec-9-enoic_acid
|
3.3.2
3.3.2.10
soluble epoxide hydrolase
|
–
–
|
|
BRENDA:
BS449106
KEGG:
R07121
MetaCyc:
RXN-12134
|
|
|
|
(12Z,9R,10S)-9,10-epoxyoctadec-12-enoate + H2O <=> (12Z)-9,10-dihydroxyoctadec-12-enoic_acid
|
3.3.2
|
–
|
|
KEGG:
R07122
|
|
|
|
(8R,9Z,12Z)-8-hydroperoxy-9,12-octadecadienoate <=> (5S,8R,9Z,12Z)-5,8-dihydroxyoctadeca-9,12-dienoate
|
4.2.1.92
hydroperoxide dehydratase
5.4.4.5
9,12-octadecadienoate 8-hydroperoxide 8R-isomerase
|
–
–
|
|
BRENDA:
BR49958
KEGG:
R09905
MetaCyc:
RXN-12757
|
|
|
|
linoleic_acid + O2 <=> (8E,10R,12Z)-10-hydroperoxy-8,12-octadecadienoate
|
1.13.11.62
linoleate 10R-lipoxygenase
|
–
|
|
BRENDA:
BR49862
KEGG:
R09811
MetaCyc:
RXN-12761
SABIO-RK:
15014
|
|
|
|
phosphatidylcholine + H2O <=> lysophosphatidylcholine + linoleic_acid
|
3.1.1.4
phospholipase A2
|
–
|
|
KEGG:
R07064
|
|
|
|
linoleic_acid + O2 <=> (9Z,11S,12Z)-11-hydroperoxyoctadeca-9,12-dienoate
|
1.13.11.45
linoleate 11-lipoxygenase
|
–
|
|
BRENDA:
BR29128
KEGG:
R05718
MetaCyc:
1.13.11.45-RXN
SABIO-RK:
5312
|
|
|
|
linoleic_acid + O2 <=> (8R,9Z,12Z)-8-hydroperoxy-9,12-octadecadienoate
|
1.13.11.60
linoleate 8R-lipoxygenase
|
–
|
|
BRENDA:
BR49860
KEGG:
R07061
MetaCyc:
RXN-12756
SABIO-RK:
7565
|
|
|
|
linoleic_acid <=> 9-cis,11-trans-linoleic_acid
|
5.2.1.5
linoleate isomerase
|
–
|
|
BRENDA:
BR214
KEGG:
R03627
MetaCyc:
LINOLEATE-ISOMERASE-RXN
|
|
|
|
linoleic_acid + O2 + NADPH + H+ <=> (12Z,9R,10S)-9,10-epoxyoctadec-12-enoate + NADP+ + H2O
|
1.14.13
1.14.14
1.14.14.1
unspecific monooxygenase
|
–
–
–
|
|
KEGG:
R07055
|
|
|
|
linoleic_acid + reduced_acceptor + O2 <=> gamma-linolenic_acid + A + H2O
|
1.14.19.3
acyl-CoA 6-desaturase
|
–
|
|
BRENDA:
BS370241
KEGG:
R07063
|
|
|
|
13(S)-HODE + NAD+ <=> 13-OxoODE + NADH + H+
|
1.1.1
|
–
|
|
KEGG:
R07058
|
|